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Incorrect or excessive usage of diazepam may result in dependence. At a very high risk for diazepam misuse, material use disorder or dependence are:Diazepam and its metabolites are excreted primarily inside the urine, predominantly as their glucuronide conjugates. The clearance of diazepam is 20 to 30 mL/min in youthful adults. Diazepam accumulates